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In scopul diminuarii acestui risc, se recomanda un somn nocturn neintrerupt. Riscul de afectare a vigilentei este mai mare daca durata somnului este insuficienta.dependenta fizica si psihica, chiar la dozele terapeutice, cu sindrom de abstinenta sau fenomen de rebound la intreruperea tratamentului;Doza este rigid individualizata, dozele
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